Current research indicates that neurotrophic factor pathway modulation serves as the primary driver of its therapeutic effects, supported by at least four additional mechanisms that work synergistically to promote neuronal survival, plasticity, and functional recovery
Additionally, in a cohort of 101,776 lung cancer cases, hypertension significantly increased mortality risk at 1-year (47.9%), 5-year (30.5%), and 10-year (28.2%) intervals compared to other non-pulmonary comorbidities [20]
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Joglar B, Rodriguez-Pallares J, Rodriguez-Perez AI, Rey P, Guerra MJ, Labandeira-Garcia JL